The prevalence of obesity and its associated co-morbidities has increased substantially in the last number of decades, and the disease is now widely considered to be a global epidemic. Currently, among approved anti-obesity therapies, only GI surgery can effectively lead to substantial weight loss results, accompanied by long-term sustainability.129 However, GI surgery has largely been rendered impractical as a useful anti-obesity strategy, in large part due to its high cost and rate of mortality. There has, however, been increasingly convincing evidence that the resulting weight loss following the surgery is due, at least in part, to an alteration in the circulating levels and physiology of certain gut hormones.1, 63 Stimulated release of anorexigenic peptides such as CCK, PP, PYY, GLP-1, and OXM, and diminished release of the orexigenic peptide ghrelin, have been documented.63 In contrast to some of the currently used, relatively non-specific drug therapies, gut hormones function specifically on systems responsible for appetite control.129 In addition, due to their natural physiological regulation of appetite, gut hormone-based therapies are less likely to cause adverse side effe میزان آگاهی شما در مورد وزن گیری دوره میانسالی وسالمندی...
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برچسب : نویسنده : sercheh بازدید : 65 تاريخ : يکشنبه 10 دی 1396 ساعت: 1:38